Ameliorative Potential of Cymbopogon citratus Dried Leaf Powder in Attenuation of Hyperlipidemia

ABSTRACT

Background and Objective: Cardiovascular disease (CHD) are the primary reason of morbidity and mortality in all around the world so this study was aimed to assess and compare the prospect of ameliorative potential of sun dried C. citratus leaf powder against lipid-lowering drugs (statins) in hyperlipidemic non-smoker male patients and also to execute its compositional analysis. Materials and Methods: C. citratus powder was firstly subjected to proximate analysis. Then nominated hyperlipidemic, non-smoker males (age 25-50 years) were divided into four groups (G₁, G₂, G₃ and G₄) and each faction included 10 subjects. First three sets were given deliberated amounts of C. citratus powder (4, 8 and 12 g, respectively) for 30 days. G₄ set was prescribed the use of statins. Serum lipid profile was analyzed of each volunteer before and after the termination of the trial. The data obtained was subjected to statistical analyses. Results: Most desirable cholesterol reduction was witnessed in G₂ and G₃ (235.90±33.20 - 187.30±47.37 and 230.60±37.43 - 182.50±35.16 mg dL^-1, respectively). Levels of TG diminished most significantly in G₄ (statins), which was from 178.70±54.40 - 131.20±31.22. LDL reduction in both G₂ and G₃ were nearly same (G₂; 15.1% and G₂; 15.7%). However, G₄ lowered the HDL level considerably from 55.30±10.91 - 35.80±4.66 mg dL^-1. Conclusion: So, it was concluded that C. citratus attenuated the serum lipid parameters dose dependently; hence, it can be considered as an arsenal for fighting against the health problems that have risen from elevated levels of lipid markers.