Phytochemical Screening of Hydroalcoholic Extract and Antimicrobial Activity of Active Principles of Eclipta alba (L.)

ABSTRACT

Background and Objectives: Plants remain a major source of medicinal compounds and in the present scenario the medicinal plants were used to confirm the pharmacological properties which perform as pioneering anti-infectious agent for many diseases. The objective of the present research was to evaluate phytogenic chemical compounds and antimicrobial activity of Eclipta alba root extract. Materials and Methods: Eclipta alba root was extracted with a hydroalcoholic solvent using the maceration process. This extract was used to determine the extraction yield, phytochemical composition and antimicrobial activity. Results: In the present study the percentage extraction yield of Eclipta alba root was 2.5% w/w using the maceration process. The phytochemical screening of extract revealed the presence of Phenols, Diterpene, Carbohydrates and Saponins. The Eclipta alba root extract was also tested for antimicrobial activity using the zone of inhibition test against Escherichia coli and Bacillus subtilis. Conclusion: The result showed that the bioactive components of Eclipta alba have enormous potential against E. coli and B. subtilis.